Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers

Ewing sarcoma (EwS) is an aggressive pediatric bone cancer in need of more effective therapies than currently available. Most research into novel targeted therapeutic approaches is focused on the fusion oncogene EWSR1-FLI1, which is the genetic hallmark of this disease. In this study, a broad range...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tsafou, Kalliopi, Katschnig, Anna Maria, Radic-Sarikas, Branka, Mutz, Cornelia Noëlle, Iljin, Kristiina, Schwentner, Raphaela, Kauer, Maximilian O., Mühlbacher, Karin, Aryee, Dave N.T., Westergaard, David, Haapa-Paananen, Saija, Fey, Vidal, Superti-Furga, Giulio, Toretsky, Jeffrey, Brunak, Søren, Kovar, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089552/
https://ncbi.nlm.nih.gov/pubmed/30123424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25760
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados