Small noncoding RNAs in FSHD2 muscle cells reveal both DUX4- and SMCHD1-specific signatures

Facioscapulohumeral muscular dystrophy (FSHD) is caused by insufficient epigenetic repression of D4Z4 macrosatellite repeat where DUX4, an FSHD causing gene is embedded. There are two forms of FSHD, FSHD1 with contraction of D4Z4 repeat and FSHD2 with chromatin compaction defects mostly due to SMCHD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Lim, Jong-Won, Wong, Chao-Jen, Yao, Zizhen, Tawil, Rabi, van der Maarel, Silvère M, Miller, Daniel G, Tapscott, Stephen J, Filippova, Galina N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048983/
https://ncbi.nlm.nih.gov/pubmed/29741619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy173
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