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Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells
Facioscapulohumeral dystrophy (FSHD) is caused by the mis-expression of the double-homeodomain transcription factor DUX4 in skeletal muscle cells. Many different cell culture models have been developed to study the pathophysiology of FSHD, frequently based on endogenous expression of DUX4 in FSHD ce...
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| Publicat a: | Hum Mol Genet |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078597/ https://ncbi.nlm.nih.gov/pubmed/28171552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw271 |
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