Mutation EthA(W21R) confers co-resistance to prothionamide and ethionamide in both Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv

Ethionamide (ETA) and prothionamide (PRO) are interchangeably used in tuberculosis (TB) chemotherapy regimens. Subtle discrepancies between biochemical and genetic information on the modes of sensitivity and resistance of isoniazid (INH) and ETA warrants further studies. We report a new mutation – E...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Infect Drug Resist
Main Authors: Mugweru, Julius, Liu, Jianxiong, Makafe, Gaelle, Chiwala, Gift, Wang, Bangxing, Wang, Changwei, Li, Xinjie, Tan, Yaoju, Yew, Wing Wai, Tan, Shouyong, Zhang, Tianyu
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Short Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005328/
https://ncbi.nlm.nih.gov/pubmed/29942141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S163965
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