EthA/R-Independent Killing of Mycobacterium tuberculosis by Ethionamide

Ethionamide (ETH) is part of the drug arsenal available to treat multi-drug resistant tuberculosis. The current paradigm of this pro-drug activation involves the mycobacterial enzyme EthA and the transcriptional repressor, EthR. However, several lines of evidence suggest the involvement of additiona...

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Publicado en:Front Microbiol
Autores principales: Ang, Michelle L. T., Zainul Rahim, Siti Z., de Sessions, Paola Florez, Lin, Wenwei, Koh, Vanessa, Pethe, Kevin, Hibberd, Martin L., Alonso, Sylvie
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403819/
https://ncbi.nlm.nih.gov/pubmed/28487681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00710
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