Mutation EthA(W21R) confers co-resistance to prothionamide and ethionamide in both Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv

Ethionamide (ETA) and prothionamide (PRO) are interchangeably used in tuberculosis (TB) chemotherapy regimens. Subtle discrepancies between biochemical and genetic information on the modes of sensitivity and resistance of isoniazid (INH) and ETA warrants further studies. We report a new mutation – E...

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發表在:Infect Drug Resist
Main Authors: Mugweru, Julius, Liu, Jianxiong, Makafe, Gaelle, Chiwala, Gift, Wang, Bangxing, Wang, Changwei, Li, Xinjie, Tan, Yaoju, Yew, Wing Wai, Tan, Shouyong, Zhang, Tianyu
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2018
主題:
Short Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005328/
https://ncbi.nlm.nih.gov/pubmed/29942141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S163965
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