Mutation EthA(W21R) confers co-resistance to prothionamide and ethionamide in both Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv

Ethionamide (ETA) and prothionamide (PRO) are interchangeably used in tuberculosis (TB) chemotherapy regimens. Subtle discrepancies between biochemical and genetic information on the modes of sensitivity and resistance of isoniazid (INH) and ETA warrants further studies. We report a new mutation – E...

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Bibliografische gegevens
Gepubliceerd in:Infect Drug Resist
Hoofdauteurs: Mugweru, Julius, Liu, Jianxiong, Makafe, Gaelle, Chiwala, Gift, Wang, Bangxing, Wang, Changwei, Li, Xinjie, Tan, Yaoju, Yew, Wing Wai, Tan, Shouyong, Zhang, Tianyu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2018
Onderwerpen:
Short Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005328/
https://ncbi.nlm.nih.gov/pubmed/29942141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S163965
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