Mutation EthA(W21R) confers co-resistance to prothionamide and ethionamide in both Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv

Ethionamide (ETA) and prothionamide (PRO) are interchangeably used in tuberculosis (TB) chemotherapy regimens. Subtle discrepancies between biochemical and genetic information on the modes of sensitivity and resistance of isoniazid (INH) and ETA warrants further studies. We report a new mutation – E...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: Mugweru, Julius, Liu, Jianxiong, Makafe, Gaelle, Chiwala, Gift, Wang, Bangxing, Wang, Changwei, Li, Xinjie, Tan, Yaoju, Yew, Wing Wai, Tan, Shouyong, Zhang, Tianyu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005328/
https://ncbi.nlm.nih.gov/pubmed/29942141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S163965
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