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T7 RNA Polymerase Discriminates Correct and Incorrect Nucleoside Triphosphates by Free Energy
RNA polymerase (RNAP) is the primary machine responsible for transcription. Its ability to distinguish between correct (cognate) and incorrect (noncognate) nucleoside triphosphates (NTPs) is important for fidelity control in transcription. In this work, we investigated the substrate selection mechan...
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| Publié dans: | Biophys J |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937113/ https://ncbi.nlm.nih.gov/pubmed/29694856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.02.033 |
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