Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases β and λ

We have recently shown that neither the base nor the sugar moieties of a nucleotide is an essential feature for its incorporation by DNA polymerases (pols) λ and β. Here we present the identification of novel non-nucleoside triphosphate (NNTP) derivatives belonging to three classes: (i) non-substrat...

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Main Authors: Crespan, Emmanuele, Alexandrova, Ludmila, Khandazhinskaya, Anastasiya, Jasko, Maxim, Kukhanova, Marina, Villani, Giuseppe, Hübscher, Ulrich, Spadari, Silvio, Maga, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2007
Assuntos:
Nucleic Acid Enzymes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1761426/
https://ncbi.nlm.nih.gov/pubmed/17148482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1016
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