DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass

The bypass of DNA lesions by the replication fork requires a switch between the replicative DNA polymerase (Pol) and a more specialized translesion synthesis (TLS) Pol to overcome the obstacle. DNA Pol δ-interacting protein 2 (PolDIP2) has been found to physically interact with Pol η, Pol ζ, and Rev...

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Main Authors: Maga, Giovanni, Crespan, Emmanuele, Markkanen, Enni, Imhof, Ralph, Furrer, Antonia, Villani, Giuseppe, Hübscher, Ulrich, van Loon, Barbara
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839753/
https://ncbi.nlm.nih.gov/pubmed/24191025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308760110
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