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Synthesis, DNA Polymerase Incorporation, and Enzymatic Phosphate Hydrolysis of Formamidopyrimidine Nucleoside Triphosphates

The nucleoside triphosphates of N6-(2-deoxy-α,β-d-erythro-pentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapy·dGTP) and its C-nucleoside analogue (β-C-Fapy·dGTP) were synthesized. The lability of the formamide group required that nucleoside triphosphate formation be carried out using a...

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Hlavní autoři: Imoto, Shuhei, Patro, Jennifer N., Jiang, Yu Lin, Oka, Natsuhisa, Greenberg, Marc M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780028/
https://ncbi.nlm.nih.gov/pubmed/17090045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja065525r
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