T7 RNA Polymerase Discriminates Correct and Incorrect Nucleoside Triphosphates by Free Energy

RNA polymerase (RNAP) is the primary machine responsible for transcription. Its ability to distinguish between correct (cognate) and incorrect (noncognate) nucleoside triphosphates (NTPs) is important for fidelity control in transcription. In this work, we investigated the substrate selection mechan...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Biophys J
Главные авторы: Wu, Shaogui, Wang, Jiayang, Pu, Xuemei, Li, Laicai, Li, Quan
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2018
Предметы:
Nucleic Acids and Genome Biophysics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937113/
https://ncbi.nlm.nih.gov/pubmed/29694856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.02.033
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы