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Origin of Ion Specificity of Telomeric DNA G-Quadruplexes Investigated by Free-Energy Simulations

Telomeric DNA consists of tandem repeats of the sequence d(TTAGGG) that form G-quadruplex structures made of stacked guanines with monovalent cations bound at a central cavity. Although different ions can stabilize a G-quadruplex structure, the preferred bound ions are typically K(+) or Na(+). Sever...

詳細記述

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書誌詳細
出版年:Biophys J
主要な著者: Siebenmorgen, Till, Zacharias, Martin
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474742/
https://ncbi.nlm.nih.gov/pubmed/28591601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.036
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