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Origin of Ion Specificity of Telomeric DNA G-Quadruplexes Investigated by Free-Energy Simulations
Telomeric DNA consists of tandem repeats of the sequence d(TTAGGG) that form G-quadruplex structures made of stacked guanines with monovalent cations bound at a central cavity. Although different ions can stabilize a G-quadruplex structure, the preferred bound ions are typically K(+) or Na(+). Sever...
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| Publicado no: | Biophys J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474742/ https://ncbi.nlm.nih.gov/pubmed/28591601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.036 |
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