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Minor Groove Deformability of DNA: A Molecular Dynamics Free Energy Simulation Study
The conformational deformability of nucleic acids can influence their function and recognition by proteins. A class of DNA binding proteins including the TATA box binding protein binds to the DNA minor groove, resulting in an opening of the minor groove and DNA bending toward the major groove. Expli...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Biophysical Society
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1563752/ https://ncbi.nlm.nih.gov/pubmed/16698780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.083816 |
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