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Minor Groove Deformability of DNA: A Molecular Dynamics Free Energy Simulation Study
The conformational deformability of nucleic acids can influence their function and recognition by proteins. A class of DNA binding proteins including the TATA box binding protein binds to the DNA minor groove, resulting in an opening of the minor groove and DNA bending toward the major groove. Expli...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biophysical Society
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1563752/ https://ncbi.nlm.nih.gov/pubmed/16698780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.083816 |
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