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Elbow Flexibility of the kt38 RNA Kink-Turn Motif Investigated by Free-Energy Molecular Dynamics Simulations

Kink-turns (K-turns) are common structural motifs that can introduce sharp kinks into double-stranded RNA, and have been proposed to mediate large-scale motions in the ribosome. K-turns consist of a bulge loop region flanked by trans sugar-Hoogsteen G:A pairs, and the sharp kink conformation is stab...

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Hlavní autoři: Curuksu, Jeremy, Sponer, Jiri, Zacharias, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756366/
https://ncbi.nlm.nih.gov/pubmed/19804732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.031
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