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Free Energy Profile of RNA Hairpins: A Molecular Dynamics Simulation Study

RNA hairpin loops are one of the most abundant secondary structure elements and participate in RNA folding and protein-RNA recognition. To characterize the free energy surface of RNA hairpin folding at an atomic level, we calculated the potential of mean force (PMF) as a function of the end-to-end d...

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Detalhes bibliográficos
Main Authors: Deng, Nan-Jie, Cieplak, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820654/
https://ncbi.nlm.nih.gov/pubmed/20159159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.040
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