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Human replication protein A unfolds telomeric G-quadruplexes
G-quadruplex structures inhibit telomerase activity and must be disrupted for telomere elongation during S phase. It has been suggested that the replication protein A (RPA) could unwind and maintain single-stranded DNA in a state amenable to the binding of telomeric components. We show here that und...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635258/ https://ncbi.nlm.nih.gov/pubmed/16973897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl564 |
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