Human replication protein A unfolds telomeric G-quadruplexes

G-quadruplex structures inhibit telomerase activity and must be disrupted for telomere elongation during S phase. It has been suggested that the replication protein A (RPA) could unwind and maintain single-stranded DNA in a state amenable to the binding of telomeric components. We show here that und...

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Bibliografiske detaljer
Main Authors: Salas, Tonatiuh Romero, Petruseva, Irina, Lavrik, Olga, Bourdoncle, Anne, Mergny, Jean-Louis, Favre, Alain, Saintomé, Carole
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Nucleic Acid Enzymes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635258/
https://ncbi.nlm.nih.gov/pubmed/16973897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl564
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