The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Age-associated changes in hematopoietic stem and progenitor cells (HSPCs) have been carefully documented in mouse models but poorly characterized in primates and humans. To investigate clinically relevant aspects of hematopoietic aging, we compared the clonal output of thousands of genetically barco...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Yu, Kyung-Rok, Espinoza, Diego A., Wu, Chuanfeng, Truitt, Lauren, Shin, Tae-Hoon, Chen, Shirley, Fan, Xing, Yabe, Idalia M., Panch, Sandhya, Hong, So Gun, Koelle, Samson, Lu, Rong, Bonifacino, Aylin, Krouse, Allen, Metzger, Mark, Donahue, Robert E., Dunbar, Cynthia E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855019/
https://ncbi.nlm.nih.gov/pubmed/29295845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-802033
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