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Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity
Gene therapies using integrating retrovirus vectors to modify hematopoietic stem and progenitor cells have shown great promise for the treatment of immune system and hematologic diseases. However, activation of proto-oncogenes via insertional mutagenesis has resulted in the development of leukemia....
Kaydedildi:
| Yayımlandı: | Mol Ther Methods Clin Dev |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Gene & Cell Therapy
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258888/ https://ncbi.nlm.nih.gov/pubmed/30547048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.10.009 |
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