Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity

Gene therapies using integrating retrovirus vectors to modify hematopoietic stem and progenitor cells have shown great promise for the treatment of immune system and hematologic diseases. However, activation of proto-oncogenes via insertional mutagenesis has resulted in the development of leukemia....

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Ther Methods Clin Dev
Asıl Yazarlar: Yabe, Idalia M., Truitt, Lauren L., Espinoza, Diego A., Wu, Chuanfeng, Koelle, Samson, Panch, Sandhya, Corat, Marcus A.F., Winkler, Thomas, Yu, Kyung-Rok, Hong, So Gun, Bonifacino, Aylin, Krouse, Allen, Metzger, Mark, Donahue, Robert E., Dunbar, Cynthia E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258888/
https://ncbi.nlm.nih.gov/pubmed/30547048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.10.009
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller