The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Age-associated changes in hematopoietic stem and progenitor cells (HSPCs) have been carefully documented in mouse models but poorly characterized in primates and humans. To investigate clinically relevant aspects of hematopoietic aging, we compared the clonal output of thousands of genetically barco...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Yu, Kyung-Rok, Espinoza, Diego A., Wu, Chuanfeng, Truitt, Lauren, Shin, Tae-Hoon, Chen, Shirley, Fan, Xing, Yabe, Idalia M., Panch, Sandhya, Hong, So Gun, Koelle, Samson, Lu, Rong, Bonifacino, Aylin, Krouse, Allen, Metzger, Mark, Donahue, Robert E., Dunbar, Cynthia E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2018
Onderwerpen:
Hematopoiesis and Stem Cells
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855019/
https://ncbi.nlm.nih.gov/pubmed/29295845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-802033
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