The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Age-associated changes in hematopoietic stem and progenitor cells (HSPCs) have been carefully documented in mouse models but poorly characterized in primates and humans. To investigate clinically relevant aspects of hematopoietic aging, we compared the clonal output of thousands of genetically barco...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Yu, Kyung-Rok, Espinoza, Diego A., Wu, Chuanfeng, Truitt, Lauren, Shin, Tae-Hoon, Chen, Shirley, Fan, Xing, Yabe, Idalia M., Panch, Sandhya, Hong, So Gun, Koelle, Samson, Lu, Rong, Bonifacino, Aylin, Krouse, Allen, Metzger, Mark, Donahue, Robert E., Dunbar, Cynthia E.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2018
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855019/
https://ncbi.nlm.nih.gov/pubmed/29295845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-802033
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