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The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Age-associated changes in hematopoietic stem and progenitor cells (HSPCs) have been carefully documented in mouse models but poorly characterized in primates and humans. To investigate clinically relevant aspects of hematopoietic aging, we compared the clonal output of thousands of genetically barco...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Blood
Κύριοι συγγραφείς: Yu, Kyung-Rok, Espinoza, Diego A., Wu, Chuanfeng, Truitt, Lauren, Shin, Tae-Hoon, Chen, Shirley, Fan, Xing, Yabe, Idalia M., Panch, Sandhya, Hong, So Gun, Koelle, Samson, Lu, Rong, Bonifacino, Aylin, Krouse, Allen, Metzger, Mark, Donahue, Robert E., Dunbar, Cynthia E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855019/
https://ncbi.nlm.nih.gov/pubmed/29295845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-802033
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