Early sensitization of myofilaments to Ca(2+) prevents genetically linked dilated cardiomyopathy in mice

BACKGROUND: Dilated cardiomoypathies (DCM) are a heterogeneous group of inherited and acquired diseases characterized by decreased contractility and enlargement of cardiac chambers and a major cause of morbidity and mortality. Mice with Glu54Lys mutation in α-tropomyosin (Tm54) demonstrate typical D...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cardiovasc Res
Hlavní autoři: Alves, Marco L., Warren, Chad M., Simon, Jillian N., Gaffin, Robert D., Montminy, Eric M., Wieczorek, David F., Solaro, R. John, Wolska, Beata M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852625/
https://ncbi.nlm.nih.gov/pubmed/28379313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx068
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky