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Spatial structure of disordered proteins dictates conductance and selectivity in nuclear pore complex mimics

Nuclear pore complexes (NPCs) lined with intrinsically disordered FG-domains act as selective gatekeepers for molecular transport between the nucleus and the cytoplasm in eukaryotic cells. The underlying physical mechanism of the intriguing selectivity is still under debate. Here, we probe the trans...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Ananth, Adithya N, Mishra, Ankur, Frey, Steffen, Dwarkasing, Arvind, Versloot, Roderick, van der Giessen, Erik, Görlich, Dirk, Onck, Patrick, Dekker, Cees
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826291/
https://ncbi.nlm.nih.gov/pubmed/29442997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31510
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