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Spatial structure of disordered proteins dictates conductance and selectivity in nuclear pore complex mimics

Nuclear pore complexes (NPCs) lined with intrinsically disordered FG-domains act as selective gatekeepers for molecular transport between the nucleus and the cytoplasm in eukaryotic cells. The underlying physical mechanism of the intriguing selectivity is still under debate. Here, we probe the trans...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Ananth, Adithya N, Mishra, Ankur, Frey, Steffen, Dwarkasing, Arvind, Versloot, Roderick, van der Giessen, Erik, Görlich, Dirk, Onck, Patrick, Dekker, Cees
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826291/
https://ncbi.nlm.nih.gov/pubmed/29442997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31510
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