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FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties

The permeability barrier of nuclear pore complexes (NPCs) controls all nucleo-cytoplasmic exchange. It is freely permeable for small molecules. Objects larger than ≈30 kDa can efficiently cross this barrier only when bound to nuclear transport receptors (NTRs) that confer translocation-promoting pro...

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Detalhes bibliográficos
Main Authors: Frey, Steffen, Görlich, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728434/
https://ncbi.nlm.nih.gov/pubmed/19680227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.199
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