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Characterisation of the passive permeability barrier of nuclear pore complexes

Nuclear pore complexes (NPCs) restrict uncontrolled nucleocytoplasmic fluxes of inert macromolecules but permit facilitated translocation of nuclear transport receptors and their cargo complexes. We probed the passive barrier of NPCs and observed sieve-like properties with a dominating mesh or chann...

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Detalhes bibliográficos
Main Authors: Mohr, Dagmar, Frey, Steffen, Fischer, Torsten, Güttler, Thomas, Görlich, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728435/
https://ncbi.nlm.nih.gov/pubmed/19680228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.200
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