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Characterisation of the passive permeability barrier of nuclear pore complexes

Nuclear pore complexes (NPCs) restrict uncontrolled nucleocytoplasmic fluxes of inert macromolecules but permit facilitated translocation of nuclear transport receptors and their cargo complexes. We probed the passive barrier of NPCs and observed sieve-like properties with a dominating mesh or chann...

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Bibliographic Details
Main Authors: Mohr, Dagmar, Frey, Steffen, Fischer, Torsten, Güttler, Thomas, Görlich, Dirk
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728435/
https://ncbi.nlm.nih.gov/pubmed/19680228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.200
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