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The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion
Nuclear pore complexes (NPCs) restrict the nucleocytoplasmic flux of most macromolecules, but permit facilitated passage of nuclear transport receptors and their cargo complexes. We found that a simple hydrophobic interaction column can mimic the selectivity of NPCs surprisingly well and that nuclea...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126029/ https://ncbi.nlm.nih.gov/pubmed/12032079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.11.2664 |
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