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Kinetic analysis of translocation through nuclear pore complexes
The mechanism of facilitated translocation through nuclear pore complexes (NPCs) is only poorly understood. Here, we present a kinetic analysis of the process using various model substrates. We find that the translocation capacity of NPCs is unexpectedly high, with a single NPC allowing a mass flow...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145537/ https://ncbi.nlm.nih.gov/pubmed/11250898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.6.1320 |
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