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Cargo surface hydrophobicity is sufficient to overcome the nuclear pore complex selectivity barrier
To fulfil their function, nuclear pore complexes (NPCs) must discriminate between inert proteins and nuclear transport receptors (NTRs), admitting only the latter. This specific permeation is thought to depend on interactions between hydrophobic patches on NTRs and phenylalanine-glycine (FG) or rela...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750018/ https://ncbi.nlm.nih.gov/pubmed/19680225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.225 |
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