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Stabilization of a protein conferred by an increase in folded state entropy

Entropic stabilization of native protein structures typically relies on strategies that serve to decrease the entropy of the unfolded state. Here we report, using a combination of experimental and computational approaches, on enhanced thermodynamic stability conferred by an increase in the configura...

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Autores principales: Dagan, Shlomi, Hagai, Tzachi, Gavrilov, Yulian, Kapon, Ruti, Levy, Yaakov, Reich, Ziv
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696814/
https://ncbi.nlm.nih.gov/pubmed/23754389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302284110
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