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Stabilization of a protein conferred by an increase in folded state entropy

Entropic stabilization of native protein structures typically relies on strategies that serve to decrease the entropy of the unfolded state. Here we report, using a combination of experimental and computational approaches, on enhanced thermodynamic stability conferred by an increase in the configura...

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Bibliographische Detailangaben
Hauptverfasser: Dagan, Shlomi, Hagai, Tzachi, Gavrilov, Yulian, Kapon, Ruti, Levy, Yaakov, Reich, Ziv
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696814/
https://ncbi.nlm.nih.gov/pubmed/23754389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302284110
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