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Stabilization of a protein conferred by an increase in folded state entropy

Entropic stabilization of native protein structures typically relies on strategies that serve to decrease the entropy of the unfolded state. Here we report, using a combination of experimental and computational approaches, on enhanced thermodynamic stability conferred by an increase in the configura...

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Detalhes bibliográficos
Main Authors: Dagan, Shlomi, Hagai, Tzachi, Gavrilov, Yulian, Kapon, Ruti, Levy, Yaakov, Reich, Ziv
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696814/
https://ncbi.nlm.nih.gov/pubmed/23754389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302284110
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