Probing the Disordered Domain of the Nuclear Pore Complex through Coarse-Grained Molecular Dynamics Simulations

The distribution of disordered proteins (FG-nups) that line the transport channel of the nuclear pore complex (NPC) is investigated by means of coarse-grained molecular dynamics simulations. A one-bead-per-amino-acid model is presented that accounts for the hydrophobic/hydrophilic and electrostatic...

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Hauptverfasser: Ghavami, Ali, Veenhoff, Liesbeth M., van der Giessen, Erik, Onck, Patrick R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2014
Schlagworte:
Molecular Machines, Motors and Nanoscale Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167297/
https://ncbi.nlm.nih.gov/pubmed/25229147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.060
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