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Probing the Disordered Domain of the Nuclear Pore Complex through Coarse-Grained Molecular Dynamics Simulations

The distribution of disordered proteins (FG-nups) that line the transport channel of the nuclear pore complex (NPC) is investigated by means of coarse-grained molecular dynamics simulations. A one-bead-per-amino-acid model is presented that accounts for the hydrophobic/hydrophilic and electrostatic...

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Detalhes bibliográficos
Main Authors: Ghavami, Ali, Veenhoff, Liesbeth M., van der Giessen, Erik, Onck, Patrick R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167297/
https://ncbi.nlm.nih.gov/pubmed/25229147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.060
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