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DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex

The nuclear pore complex (NPC) is the gatekeeper for nuclear transport in eukaryotic cells. A key component of the NPC is the central shaft lined with intrinsically disordered proteins (IDPs) known as FG-Nups, which control the selective molecular traffic. Here, we present an approach to realize art...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Ketterer, Philip, Ananth, Adithya N., Laman Trip, Diederik S., Mishra, Ankur, Bertosin, Eva, Ganji, Mahipal, van der Torre, Jaco, Onck, Patrick, Dietz, Hendrik, Dekker, Cees
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834454/
https://ncbi.nlm.nih.gov/pubmed/29500415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03313-w
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