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Uncovering the forces between nucleosomes using DNA origami

Revealing the energy landscape for nucleosome association may contribute to the understanding of higher-order chromatin structures and their impact on genome regulation. We accomplish this in a direct measurement by integrating two nucleosomes into a DNA origami–based force spectrometer, which enabl...

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Publicat a:Sci Adv
Autors principals: Funke, Jonas J., Ketterer, Philip, Lieleg, Corinna, Schunter, Sarah, Korber, Philipp, Dietz, Hendrik
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262459/
https://ncbi.nlm.nih.gov/pubmed/28138524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600974
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