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Uncovering the forces between nucleosomes using DNA origami
Revealing the energy landscape for nucleosome association may contribute to the understanding of higher-order chromatin structures and their impact on genome regulation. We accomplish this in a direct measurement by integrating two nucleosomes into a DNA origami–based force spectrometer, which enabl...
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| Veröffentlicht in: | Sci Adv |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Association for the Advancement of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5262459/ https://ncbi.nlm.nih.gov/pubmed/28138524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600974 |
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