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Spatial structure of disordered proteins dictates conductance and selectivity in nuclear pore complex mimics
Nuclear pore complexes (NPCs) lined with intrinsically disordered FG-domains act as selective gatekeepers for molecular transport between the nucleus and the cytoplasm in eukaryotic cells. The underlying physical mechanism of the intriguing selectivity is still under debate. Here, we probe the trans...
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| Pubblicato in: | eLife |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826291/ https://ncbi.nlm.nih.gov/pubmed/29442997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31510 |
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