Anti‐Parkinsonian and anti‐dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists

BACKGROUND AND PURPOSE: We previously showed that nociceptin/orphanin FQ opioid peptide (NOP) receptor agonists attenuate the expression of levodopa‐induced dyskinesia in animal models of Parkinson's disease. We now investigate the efficacy of two novel, potent and chemically distinct NOP recep...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Arcuri, Ludovico, Novello, Salvatore, Frassineti, Martina, Mercatelli, Daniela, Pisanò, Clarissa Anna, Morella, Ilaria, Fasano, Stefania, Journigan, Blair V, Meyer, Michael E, Polgar, Willma E, Brambilla, Riccardo, Zaveri, Nurulain T, Morari, Michele
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811622/
https://ncbi.nlm.nih.gov/pubmed/29232769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14123
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