Anti‐Parkinsonian and anti‐dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists

BACKGROUND AND PURPOSE: We previously showed that nociceptin/orphanin FQ opioid peptide (NOP) receptor agonists attenuate the expression of levodopa‐induced dyskinesia in animal models of Parkinson's disease. We now investigate the efficacy of two novel, potent and chemically distinct NOP recep...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Arcuri, Ludovico, Novello, Salvatore, Frassineti, Martina, Mercatelli, Daniela, Pisanò, Clarissa Anna, Morella, Ilaria, Fasano, Stefania, Journigan, Blair V, Meyer, Michael E, Polgar, Willma E, Brambilla, Riccardo, Zaveri, Nurulain T, Morari, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811622/
https://ncbi.nlm.nih.gov/pubmed/29232769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14123
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