Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10

Cleavage of membrane-anchored proteins by ADAM (a disintegrin and metalloproteinase) endopeptidases plays a key role in a wide variety of biological signal transduction and protein turnover processes. Among ADAM family members, ADAM10 stands out as particularly important because it is both responsib...

詳細記述

保存先:
書誌詳細
出版年:Cell
主要な著者: Seegar, Tom C.M., Killingsworth, Lauren B., Saha, Nayanendu, Meyer, Peter A., Patra, Dhabaleswar, Zimmerman, Brandon, Janes, Peter W., Rubinstein, Eric, Nikolov, Dimitar B., Skiniotis, Georgios, Kruse, Andrew C., Blacklow, Stephen C.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773094/
https://ncbi.nlm.nih.gov/pubmed/29224781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.11.014
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