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Domain integration of ADAM family proteins: Emerging themes from structural studies

ADAM (a disintegrin and metalloproteinase) proteins are type-1 transmembrane and secreted proteins that function in cell adhesion and signal transduction. Here we review the structural features of ADAM proteins that direct their biological functions in ectodomain shedding and cell adhesion. IMPACT S...

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Détails bibliographiques
Publié dans:Exp Biol Med (Maywood)
Auteurs principaux: Seegar, Tom CM, Blacklow, Stephen C
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920674/
https://ncbi.nlm.nih.gov/pubmed/31333048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219865901
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