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Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition

Post-synaptic density-95, disks-large and zonula occludens-1 (PDZ) domains are small globular protein–protein interaction domains widely conserved from yeast to humans. They are composed of ∼90 amino acids and form a classical two α-helical/six β-strand structure. The prototypical ligand is the C-te...

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Detalhes bibliográficos
Publicado no:Int Rev Cell Mol Biol
Main Authors: Liu, Xu, Fuentes, Ernesto J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185565/
https://ncbi.nlm.nih.gov/pubmed/30712672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ircmb.2018.05.013
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