Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition

od Liu, Xu, Fuentes, Ernesto J.
izdano v Int Rev Cell Mol Biol (2019)

Structural and Thermodynamic Analysis of PDZ–Ligand Interactions

od Shepherd, Tyson R., Fuentes, Ernesto J.
Izdano 2011

High-resolution structure of the Tiam1 PH(n)-CC-Ex domain

od Joshi, Monika, Gakhar, Lokesh, Fuentes, Ernesto J.
Izdano 2013

Conservation of Side-Chain Dynamics Within a Protein Family

od Law, Anthony B., Fuentes, Ernesto J., Lee, Andrew L.
Izdano 2009

Accurate PDZ/Peptide Binding Specificity with Additive and Polarizable Free Energy Simulations

od Panel, Nicolas, Villa, Francesco, Fuentes, Ernesto J., Simonson, Thomas
izdano v Biophys J (2018)

A Simple PB/LIE Free Energy Function Accurately Predicts the Peptide Binding Specificity of the Tiam1 PDZ Domain

od Panel, Nicolas, Sun, Young Joo, Fuentes, Ernesto J., Simonson, Thomas
izdano v Front Mol Biosci (2017)

The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain

od Xu, Zhen, Gakhar, Lokesh, Bain, Fletcher E., Spies, Maria, Fuentes, Ernesto J.
izdano v J Biol Chem (2017)

The Structure of the Tiam1 PDZ Domain/Phospho-Syndecan1 Complex Reveals a Ligand Conformation that Modulates Protein Dynamics

od Liu, Xu, Shepherd, Tyson R., Murray, Ann M., Xu, Zhen, Fuentes, Ernesto J.
Izdano 2013

Hidden dynamic allostery in a PDZ domain

od Petit, Chad M., Zhang, Jun, Sapienza, Paul J., Fuentes, Ernesto J., Lee, Andrew L.
Izdano 2009

Distinct Ligand Specificity of the Tiam1 and Tiam2 PDZ Domains

od Shepherd, Tyson R., Hard, Ryan L., Murray, Ann M., Pei, Dehua, Fuentes, Ernesto J.
Izdano 2011

Chemosensory Regulation of a HEAT-Repeat Protein Couples Aggregation and Sporulation in Myxococcus xanthus

od Darnell, Cynthia L., Wilson, Janet M., Tiwari, Nitija, Fuentes, Ernesto J., Kirby, John R.
Izdano 2014

A physics-based energy function allows the computational redesign of a PDZ domain

od Opuu, Vaitea, Sun, Young Joo, Hou, Titus, Panel, Nicolas, Fuentes, Ernesto J., Simonson, Thomas
izdano v Sci Rep (2020)

FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phase arrest

od Wen, Hsiang, Kim, Namhun, Fuentes, Ernesto J, Mallinger, Adam, Gonzalez-Alegre, Pedro, Glenn, Kevin A
Izdano 2010

The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell-Matrix Adhesion

od Shepherd, Tyson R., Klaus, Suzi M., Liu, Xu, Ramaswamy, S., DeMali, Kris A., Fuentes, Ernesto J.
izdano v J Mol Biol (2010)

Conformational Dynamics and Cooperativity Drive the Specificity of a Protein-Ligand Interaction

od Liu, Xu, Golden, Lisa C., Lopez, Josue A., Shepherd, Tyson R., Yu, Liping, Fuentes, Ernesto J.
izdano v Biophys J (2019)

A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress

od Liu, Yunhao, Collins, Caitlin, Kiosses, William B., Murray, Ann M., Joshi, Monika, Shepherd, Tyson R., Fuentes, Ernesto J., Tzima, Ellie
Izdano 2013

Specificity Residues Determine Binding Affinity for Two-Component Signal Transduction Systems

od Willett, Jonathan W., Tiwari, Nitija, Müller, Susanne, Hummels, Katherine R., Houtman, Jon C. D., Fuentes, Ernesto J., Kirby, John R.
Izdano 2013

The Staphylococcus aureus ArlRS two-component system regulates virulence factor expression through MgrA

od Crosby, Heidi A., Tiwari, Nitija, Kwiecinski, Jakub M., Xu, Zhen, Dykstra, Allison, Jenul, Christian, Fuentes, Ernesto J, Horswill, Alexander R.
izdano v Mol Microbiol (2019)

Distinct Roles for Conformational Dynamics in Protein-ligand Interactions

od Liu, Xu, Speckhard, David C., Shepherd, Tyson R., Sun, Young Joo, Hengel, Sarah R., Yu, Liping, Fowler, C. Andrew, Gakhar, Lokesh, Fuentes, Ernesto J.
izdano v Structure (2016)

SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility

od Awadia, Sahezeel, Huq, Farah, Arnold, Torey R., Goicoechea, Silvia M., Sun, Young Joo, Hou, Titus, Kreider-Letterman, Gabriel, Massimi, Paola, Banks, Lawrence, Fuentes, Ernesto J., Miller, Ann L., Garcia-Mata, Rafael
izdano v J Cell Biol (2019)