FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phase arrest

During cell proliferation, protein degradation is strictly regulated by the cell cycle and involves two complementary ubiquitin ligase complexes, the SCF (Skp, Cullin, F-box) and APC/C (Anaphase Promoting Complex/Cyclosome) ubiquitin ligases. SCF ligases are constitutively active and generally targe...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Wen, Hsiang, Kim, Namhun, Fuentes, Ernesto J, Mallinger, Adam, Gonzalez-Alegre, Pedro, Glenn, Kevin A
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2010
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048047/
https://ncbi.nlm.nih.gov/pubmed/21135578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.22.13743
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki