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APC/C ubiquitin ligase: functions and mechanisms in tumorigenesis

The anaphase promoting complex/ cyclosome (APC/C), is an evolutionarily conserved protein complex essential for cellular division due to its role in regulating the mitotic transition from metaphase to anaphase. In this review, we highlight recent work that has shed light on our understanding of the...

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Detalhes bibliográficos
Publicado no:Semin Cancer Biol
Main Authors: Schrock, Morgan S., Stromberg, Benjamin R., Scarberry, Luke, Summers, Matthew K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483777/
https://ncbi.nlm.nih.gov/pubmed/32165320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2020.03.001
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