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Activation of the APC/C Ubiquitin Ligase by Enhanced E2 Efficiency
The anaphase-promoting complex/cyclosome (APC/C) is a protein-ubiquitin ligase (E3) that initiates the final events of mitosis by catalyzing the ubiquitination and proteasomal destruction of securin, cyclins, and other substrates [1, 2]. Like other members of the RING family of E3s [3, 4], the APC/C...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090254/ https://ncbi.nlm.nih.gov/pubmed/24930963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.05.052 |
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