The Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human Cancers

A normal evolution of the cell-cycle phases consists of multiple consecutive events, which makes it a highly complex process. Its preservation is regulated by Cyclin-Cdks (cyclin-dependent kinases) interactions and protein degradation, which is often controlled by the ubiquitin-mediated proteolysis....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clujul Med
Hauptverfasser: BOCHIS, OVIDIU VASILE, FETICA, BOGDAN, VLAD, CATALIN, ACHIMAS-CADARIU, PATRICIU, IRIMIE, ALEXANDRU
Format: Artigo
Sprache:Inglês
Veröffentlicht: Iuliu Hatieganu University of Medicine and Pharmacy 2015
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508606/
https://ncbi.nlm.nih.gov/pubmed/26528041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15386/cjmed-377
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