SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility

The canonical Scribble polarity complex is implicated in regulation of epithelial junctions and apical polarity. Here, we show that SGEF, a RhoG-specific GEF, forms a ternary complex with Scribble and Dlg1, two members of the Scribble complex. SGEF targets to apical junctions in a Scribble-dependent...

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Foilsithe in:J Cell Biol
Main Authors: Awadia, Sahezeel, Huq, Farah, Arnold, Torey R., Goicoechea, Silvia M., Sun, Young Joo, Hou, Titus, Kreider-Letterman, Gabriel, Massimi, Paola, Banks, Lawrence, Fuentes, Ernesto J., Miller, Ann L., Garcia-Mata, Rafael
Formáid: Artigo
Teanga:Inglês
Foilsithe: Rockefeller University Press 2019
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683736/
https://ncbi.nlm.nih.gov/pubmed/31248911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811114
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