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SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility

The canonical Scribble polarity complex is implicated in regulation of epithelial junctions and apical polarity. Here, we show that SGEF, a RhoG-specific GEF, forms a ternary complex with Scribble and Dlg1, two members of the Scribble complex. SGEF targets to apical junctions in a Scribble-dependent...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Awadia, Sahezeel, Huq, Farah, Arnold, Torey R., Goicoechea, Silvia M., Sun, Young Joo, Hou, Titus, Kreider-Letterman, Gabriel, Massimi, Paola, Banks, Lawrence, Fuentes, Ernesto J., Miller, Ann L., Garcia-Mata, Rafael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683736/
https://ncbi.nlm.nih.gov/pubmed/31248911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811114
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